Fig. 5

Nuclear receptor expression in the developing human fetal ovary. (a) Venn diagram showing overlapping differential gene expression analyses of nuclear receptors (NRs): ovary v control, ovary v testis, testis v control, testis v ovary (log₂FC > 0.5, p.adj < 0.05). Ovary-, testis-, and gonad-specific NRs are identified. (b) Heatmap showing differentially expressed NRs across the geneset (log₂FC > 0.5, p.adj < 0.05). (c) Selected highly expressed NRs localized to UMAPs from snRNA-seq data (upper panels) and as violin plots over time in the bulk RNAseq data (lower panels). See Fig. 3 for cluster annotation.