Table 8 Average RMSD, Rg, Hbond, and RMSF values of RdRp receptor-unbound and drug-receptor complex RdRp DENV-2.

From: Repurposing FDA-approved drugs and natural compounds to inhibit the RNA-dependent RNA polymerase domain of dengue virus 2 or dengue virus 3

Num.

Compounds

RMSD

Gyrate

Hbond

RMSF

1

Chlortalidone

0.228

2.56

2.9

0.133

2

Clofazimine

0.156

2.56

0.23

0.124

3

Lumacaftor

0.195

2.55

1.3

0.141

4

Valdecoxib

0.225

2.54

2.1

0.126

5

ZINC01532028

0.203

2.56

2.9

0.134

6

ZINC01619649

0.193

2.54

2.06

0.126

7

ZINC13378516

0.239

2.53

0.59

0.137

8

ZINC14824819

0.207

2.55

1.53

0.134

9

ZINC95913991

0.217

2.55

0.78

0.124

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