Fig. 5 | Scientific Reports

Fig. 5

From: Rapid formulation of a genetically diverse phage cocktail targeting uropathogenic Escherichia coli infections using the UTI89 model

Fig. 5

The combination of phages SR02 and SR04 efficiently suppresses the growth of uropathogenic E. coli UTI89 in vitro. (a) Killing curve of the phage cocktail at different multiplicity of infections (MOIs), ranging from 1–100, against uropathogenic E. coli UTI89 during 48 h of incubation. The concentration of (b) surviving bacteria and (c) viable phages at 0, 16, 24, and 48 h during the phage cocktail treatment. The data shown in (a-c) represent the mean with a standard deviation of at least three biological replicates. According to one-way ANOVA followed by Tukey’s HSD post hoc test, asterisks represent the p-value (**p < 0.01 and ***p < 0.001) and n.s. represents a non-significant difference.

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