Table 1 – Clinical and echocardiographic characteristics at 6 months of the animals in the control group versus the Chagas group.

From: Effect of neurohormonal therapeutic in left ventricle global and regional function in Chagas cardiomyopathy in a translational animal experimental model

 

Control (n = 9)

Chagas (n = 38)

p

Weight (g)

173.8 ± 17.4

179.7 ± 18.2

0.4

HR (bpm)

159.4 ± 17.3

168.5 ± 30,4

0.2

ECHOCARDIOGRAPHY

LVEDD (mm)

7.1 ± 0.7

7.7 ± 0,6

0.02

LVESD (mm)

5.3 ± 0,9

5.7 ± 0,5

0.1

LVEF- 2D (%)

47.9 ± 6.0

44.6 ± 7.5

0.3

LVEF (MMode)

47.6 ± 11.3

48.3 ± 6.8

0.8

LVEF (Strain)

46.4 ± 6.0

44.9 ± 5.4

0.5

LV mass (i) (mg/hg)

278.4 ± 33,9

349.9 ± 55.7

0.0001

GLS (%)

− 13.3 ± 1,9

− 12.4 ± 5,9

0.5

WMSi

1.00

1.06

0.07

  1. LVEDD: left ventricle end−diastolic dimension; LVESD: left ventricle end−systolic dimension; LVEF: left ventricle ejection fraction; LV mass i: left ventricle mass indexed to weight; GLS: global longitudinal strain; WMSi: wall motion score index. Comparisons between groups with the Mann−Whitney test.
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