Table 2 Measurement of ventricular geometry and function over the follow-up of control and Chagas groups.
Variables | Control (n = 9) | Chagas (n = 12) | Ch + BB (n = 13) | Ch + ACEi (n = 13) | p (mixed-ANOVA) | |
|---|---|---|---|---|---|---|
LVEDD (mm) | 6 m | 7.1 ± 0.7 | 7.8 ± 0.9 | 7.7 ± 0.4 | 7.5 ± 0.3 | 0.9 |
8 m | 7.4 ± 0.8 | 8.1 ± 0.5 | 8.0 ± 0.5 | 7.9 ± 0.8 | ||
LVESD (mm) | 6 m | 5.3 ± 0.9 | 5.8 ± 0.7 | 5.7 ± 0.3 | 5.6 ± 0.5 | 0.1 |
8 m | 5.2 ± 0.9 | 6.2 ± 0.6 | 6.3 ± 0.6 | 6.2 ± 1.0 | ||
LVEF- 2D (%) | 6 m | 47.8 ± 6.0 | 45.3 ± 8.9 | 44.2 ± 7.4 | 44.4 ± 6.7 | 0.4 |
8 m | 46.6 ± 6.3 | 41.3 ± 13.6 | 39.2 ± 7.7 | 34.4 ± 9.7 | ||
LVEF-MMode (%) | 6 m | 49.6 ± 6.0 | 46.8 ± 8.5 | 48.3 ± 6.0 | 49.6 ± 6.0 | 0.006 |
8 m | 40.5 ± 8.7 | 44.6 ± 6.6 § | 41.6 ± 7.1 § | 40.5 ± 8.7 §* | ||
LVEF-Strain (%) | 6 m | 46.4 ± 6.0 | 43.4 ± 5.5 | 45.5 ± 6.0 | 45.6 ± 4.7 | 0.009 |
8 m | 47.6 ± 4.7 | 39.3 ± 5.3 § | 38.3 ± 5.9 §* | 34.8 ± 7.2 §* | ||
FS (%) | 6 m | 25.3 ± 6.8 | 24.5 ± 5.2 | 25.3 ± 3.9 | 26.0 ± 3.7 | 0.01 |
8 m | 24.5 ± 5.2 | 22.8 ± 3.9 § | 21.3 ± 4.1 § | 20.7 ± 5.2 §* | ||
LV mass (i) (g/hg) | 6 m | 278.4 ± 33.9 | 362.1 ± 39.2 | 320.0 ± 65.3 | 368.6 ± 49.0 | 0.2 |
8 m | 319.3 ± 49.7 | 371.4 ± 43.4 | 364.4 ± 63.4 | 363.8 ± 73.8 | ||
GLS (%) | 6 m | − 14.0 ± 2.0 | − 10.2 ± 9.3 | − 13.4 ± 3.2 | − 13.5 ± 3.4 | 0.5 |
8 m | − 11.0 ± 7.9 | − 10.6 ± 3.3 | − 10.8 ± 2.8 | − 9.9 ± 3.2 | ||
WMSi | 6 m | 1.0 ± 0.00 | 1.05 ± 0.11 | 1.05 ± 0.11 | 1.07 ± 0.10 | 0.03 |
8 m | 1.0 ± 0.00 # | 1.21 ± 0.15 * | 1.08 ± 0.09 # | 1.09 ± 0.16 | ||
HR (bpm) | 6 m | 159.4 ± 17.2 | 180.3 ± 42.2 | 167.8 ± 22.7 | 158.3 ± 21.2 | 0.2 |
8 m | 146.4 ± 22.3 | 166.3 ± 15.8 | 167.3 ± 23.4 | 178.9 ± 48.3 |
