Table 3 Univariable and multivariable logistic regression models for ORR.

From: Evaluation of the efficacy and predictive indicators of PD- 1 inhibitors combined with chemotherapy in advanced pancreatic cancer

Characteristics

Total

(N)

Univariate analysis

Multivariate analysis

Odds Ratio (95% CI)

P value

Odds Ratio (95% CI)

P value

Gender

57

    

Male

35

1

0.794

  

Female

22

0.857 (0.269–2.731)

  

Age

57

    

< 64

28

1

0.436

  

≥ 64

29

0.633 (0.201–1.996)

  

ECOG PS

57

    

0

14

1

0.002

1

0.020

1

43

7.875 (2.070–29.957)

19.210 (1.605–229.960)

Liver metastasis

57

    

Yes

34

1

0.004

1

0.017

No

23

0.158 (0.045–0.553)

0.066 (0.007–0.618)

CA199 (0 W)

57

    

≤ 37 IU/ml

14

1

0.064

  

> 37 IU/ml

43

3.300 (0.932–11.682)

  

CA199 (8w) down

57

    

Up

27

1

0.083

  

Down

30

0.341 (0.101–1.149)

  

Treatment administration

57

    

CT

29

1

0.040

1

0.034

ICT

28

0.278 (0.082–0.941)

0.096 (0.011–0.836)

SOD (0w)

57

    

≥ 154 KU/L

28

1

0.010

1

0.289

< 154 KU/L

29

5.417 (1.490–19.689)

3.114 (0.382–25.376)

SOD (8w)

57

    

Down

32

1

0.002

1

0.027

Up

25

0.132 (0.036–0.488)

0.099 (0.013–0.774)

Diabetes history

57

    

No

33

1

0.211

  

Yes

24

2.171 (0.645–7.310)

  

CEA (0w)

57

    

≤ 5 ng/ml

24

1

0.926

  

> 5 ng/ml

33

0.947 (0.299–2.995)

  

CEA (8w)

57

    

Up

26

1

0.661

  

Down

31

0.774 (0.245–2.439)