Fig. 1 | Scientific Reports

Fig. 1

From: Alterations in fecal microbiota composition and cytokine expression profiles in adolescents with depression: a case-control study

Fig. 1

Comparison of the overall structure of the fecal microbiota between adolescents with major depressive disorder (MDD) and healthy controls. (A–E) α-diversity indices (Shannon and Simpson) and richness indices (ACE, Chao1, and observed species) were utilized to assess the overall structure of fecal microbiota. Data are presented as mean ± standard deviation. Unpaired two-tailed t-tests were employed for inter-group comparisons. (F) A Venn diagram illustrates the overlap of OTUs between microbiota associated with adolescent MDD and healthy controls. (G–J) Principal coordinate analysis (PCoA) plots illustrate β-diversity of individual fecal microbiota based on Bray–Curtis, Jaccard, unweighted UniFrac, and weighted UniFrac distances. Each symbol represents a sample. (K) Rank abundance curves depict the distribution of bacterial OTUs in the two groups.

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