Fig. 7

Adolescent MDD-associated immune dysfunction. Concentrations (mean ± SEM, pg/ml) of 27 pro- and anti-inflammatory cytokines and chemokines measured in adolescent MDD patients and healthy controls using Bio-Plex immunoassays. The results indicate significant increases in the levels of IL-5 (A), Eotaxin (B), IP-10 (C), MCP-1 (D), RANTES (E), and TNF-α (F) in adolescent MDD patients relative to healthy controls (*p < 0.05; **p < 0.01; ***p < 0.001).