Fig. 1

Divergent association between choroid plexus calcium and hippocampal volume in APOE4 carriers vs. non-carriers. Scatter plot showing the relationship between CP calcium volume and hippocampal volume, both normalized by total intracranial volume, stratified by APOE4 status. The differing slopes illustrate the significant interaction between CP calcium and APOE4 status observed in the regression analysis, after adjusting for additional variables.