Fig. 2

Correlation Analysis of Vit B12 levels between different assays. Figure 2 illustrates the correlation analysis of Vit B12 levels between different assays, assessing the strength of the relationship between LC-MS/MS and three CLIA-based methods using Spearman’s rank correlation coefficients (r). Plot A presents the correlation between Accre 8 and LC-MS/MS (r = 0.94, p < 0.001), while Plot B shows the correlation between Accre 8 and Roche (r = 0.94, p < 0.001). Plot C displays the correlation between Accre 8 and Abbott (r = 0.94, p < 0.001). Plot D illustrates the correlation between Abbott and LC-MS/MS (r = 0.94, p < 0.001), whereas Plot E presents the strongest correlation between Roche and LC-MS/MS (r = 0.98, p < 0.001). Each plot includes a diagonal reference line (y = x) for visual assessment of agreement.