Table 1 Summary of Results - Intraoperative intracranial pressure (ICP) monitoring, surgical duration, postoperative mortality, success rate, and neurological assessment.

From: A modified surgical approach to induce circle Willis perforation in mice using the common carotid artery

Group

ICP Base (mmHg)

ICP Peak (mmHg)

ICP Post peak (mmHg)

Surgical Duration (Minutes)

Mortality

(%)

Success Rate

(%)

Rotarod Test (Seconds)

Open-field Test

Body Weight Loss (%)

CCAΣ

10.4 ± 3.5

n = 12

53.5 ± 10.6

n = 12

25.8 ± 4.0

n = 12

36 ± 10

n = 12

8.33

100

121 ± 78

n = 5

327 ± 224

n = 5

10.05 ± 2.47

n = 5

ECA

9.5 ± 3.0

n = 10

51.1 ± 12.6

n = 10

28.9 ± 4.9

n = 10

73 ± 18

n = 10

0

83.33

158 ± 67

n = 5

389 ± 373

n = 5

10.08 ± 3.44

n = 5

SHAM

--

--

--

15 ± 5

n = 3

0

--

289 ± 12

n = 3

1156 ± 163

n = 3

1.87 ± 0.59

n = 3

  1. The results of open-field test were recorded by using absolute value of the moving distance without units.
  2. ΣOne mouse from the CCA group died on the postoperative day one, its intraoperative data was still valid.