Fig. 1 | Scientific Reports

Fig. 1

From: Identification of serum metabolite biomarkers and metabolic reprogramming mechanisms to predict recurrence in cholangiocarcinoma

Fig. 1

Chemometrics analysis of metabolomics data. The OPLS-DA score plots for metabolites in positive (A) and negative (B) modes, with permutation tests to assess model robustness and stability. VIP plots of the top 15 metabolites in positive (C) and negative (D) modes, highlighting key metabolites contributing to group separation. Volcano plots of metabolites in positive (E) and negative (F) modes, displaying significant metabolites between the groups.

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