Table 1 Demographic information and clinical characteristics.
From: Associations of serum MANF with severity and prognosis in community-acquired pneumonia patients
Characteristic | Tertiles of Log MANF | P | ||
|---|---|---|---|---|
T1 (<3.15) | T2 (3.15 ~ 3.33) | T3 (>3.33) | ||
N | 106 | 107 | 106 | Â |
Age, years | 61.7 ± 1.84 | 57.6 ± 1.57 | 59.5 ± 1.88 | 0.262 |
Male, n (%) | 49 (46.2) | 53 (49.5) | 71 (67.0) | 0.005 |
Body mass index | 22.1 ± 0.52 | 21.9 ± 0.36 | 22.1 ± 0.39 | 0.883 |
Streptococcus pneumonae, n (%) | 41 (38.7) | 38 (35.5) | 37 (34.9) | 0.828 |
Legionella pneumophila, n (%) | 9 (8.5) | 11 (10.3) | 7 (6.6) | 0.939 |
Respiratory virus, n (%) | 3 (2.8) | 5 (4.7) | 6 (5.7) | 1.077 |
Others, n (%) | 53 (50.0) | 53 (49.5) | 50 (47.2) | 0.195 |
Hypertension, n (%) | 30 (28.3) | 27 (25.2) | 32 (30.2) | 0.726 |
Diabetes mellitus, n (%) | 12 (11.3) | 10 (9.3) | 6 (5.7) | 0.341 |
Cerebral infarction, n (%) | 13 (12.3) | 6 (5.6) | 12 (11.3) | 0.200 |
Coronary heart disease, n (%) | 2 (1.9) | 4 (3.7) | 8 (7.5) | 0.136 |
Bronchitis, n (%) | 1 (0.9) | 2 (1.9) | 3 (2.8) | 0.706 |
White blood cell (109/L) | 8.3 ± 0.47 | 7.4 ± 0.37 | 7.9 ± 0.39 | 0.331 |
Neutrophil (109/L) | 6.4 ± 0.45 | 6.1 ± 0.81 | 7.4 ± 1.18 | 0.515 |
Lymphocyte (109/L) | 1.2 ± 0.06 | 1.5 ± 0.11 | 1.3 ± 0.11 | 0.107 |
Monocyte (109/L) | 0.6 ± 0.05 | 0.6 ± 0.02 | 0.6 ± 0.03 | 0.948 |
Eosinophil (109/L) | 0.10 ± 0.01 | 0.14 ± 0.03 | 0.11 ± 0.01 | 0.451 |
Basophil (109/L) | 0.02 (0.01, 0.03) | 0.02 (0.01, 0.03) | 0.02 (0.01, 0.03) | 0.516 |
Alanine aminotransferase (U/L) | 18.0 (11.0, 33.0) | 20.0 (13.0, 37.0) | 22.5 (14.3, 35.8) | 0.060 |
Aspartate aminotransferase (U/L) | 21.0 (17.0, 32.0) | 24.0 (17.0, 33.0) | 23.0 (19.0, 36.0) | 0.355 |
Uric acid (µmol/L) | 269.5 (195.8, 375.6) | 259.0 (199.0, 331.0) | 279.0 (211.0, 325.8) | 0.598 |
Urea nitrogen (mmol/L) | 5.6 (4.0, 7.9) | 4.9 (3.9, 6.6) | 5.0 (3.9, 6.3) | 0.119 |
Creatinine (µmol/L) | 54.5 (50.0, 87.3) | 57.0 (48.0, 70.0) | 63.0 (52.6, 76.5) | 0.032 |
Creatine kinase (U/L) | 60.0 (38.0, 97.0) | 57.0 (33.0, 100.5) | 64.0 (43.8, 107.5) | 0.754 |
Creatine kinase isoenzyme (U/L) | 13.0 (8.0, 17.0) | 10.0 (8.0, 16.5) | 13.0 (9.8, 17.3) | 0.231 |
Myoglobin (ng/mL) | 41.2 (25.8, 119.2) | 29.9 (21.6, 49.5) | 32.3 (20.6, 78.6) | 0.148 |
Cardiac troponin I (ng/mL) | 0.02 (0.01, 0.11) | 0.01 (0.01, 0.04) | 0.01 (0.01, 0.97) | 0.976 |
Lactate dehydrogenase (U/L) | 194.5 (153.0, 252.5) | 190.0 (165.8, 230.3) | 202.0 (166.0, 281.0) | 0.457 |
Procalcitonin (ng/L) | 0.08 (0.03, 0.36) | 0.06 (0.02, 0.20) | 0.08 (0.02, 0.66) | 0.111 |
D-dimer (mg/L) | 1.2 (0.5, 2.5) | 0.6 (0.4, 1.3) | 0.6 (0.4, 1.4) | 0.005 |
C-reactive protein (mg/L) | 35.6 (9.2, 143.3) | 39.1 (5.6, 104.7) | 62.3 (12.3, 153.9) | 0.040 |
Interleukin-6 (pg/mL) | 16.6 (3.8, 52.7) | 14.3 (4.3, 41.7) | 23.1 (6.4, 52.0) | 0.016 |
