Fig. 5 | Scientific Reports

Fig. 5

From: Salivary chemokines and growth factors in patients with ischemic stroke

Fig. 5

Graphical conclusions of the study (generated using canva.com and biorender.com). In the unstimulated saliva of stroke patients, a significantly higher content of chemotactic factors (CTACK/CCL27, IL-8/CXCL8, MIG/CXCL9, MIF) and growth factors (basic FGF, G-CSF, HGF, LIF, VEGF) was found compared to individuals from the control group. The content of MCP-3/CCL7, eotaxin/CCL11, IP-10/CXCL10, IL-3/MCGF and PDGF-BB was significantly lower in the saliva of patients from the study group. MCP-3/CCL7: monocyte chemoattractant protein-3/chemokine ligands 7; Eotaxin/CCL11: eotaxin/chemokine ligand 11; CTACK/CCL27: cutaneous T-cell-attracting chemokine/chemokine ligands 27; IL-8/CXCL8: interleukin 8/chemokine (C-X-C motif) ligand 8; MIG/CXCL9: monokine induced by gamma interferon/chemokine (C-X-C motif) ligand 9; IP-10/CXCL10: interferon gamma-induced protein 10/chemokine (C-X-C motif) ligand 10; MIF: Macrophage migration inhibitory factor; Basic FGF: fibroblast growth factor; G-CSF: granulocyte colony-stimulating factor, HGF: Hepatocyte growth factor; IL-3/MCGF: Interleukin-3/Mast cell growth factor; LIF: Leukemia inhibitory factor; PDGF-BB; platelet-derived growth factor isoform BB; VEGF: vascular endothelial growth factor.

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