Table 3 Association between Cer(d18:1/16:0) and ACS.

From: Cer(d18:1/16:0) as a biomarkers for acute coronary syndrome in Chinese populations

Characteristic

Model 1

Model 2

Model 3

 

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

Cer(d18:1/16:0) as a continuous variable

 Cer(d18:1/16:0)

1.02 (1.01, 1.02)

 < 0.001

1.01 (1.01, 1.02)

 < 0.001

1.03 (1.01, 1.04)

 < 0.001

 Cer(d18:1/16:0) (per 1SD)

2.15 (1.73, 2.45)

 < 0.001

2.13 (1.79, 2.53)

 < 0.001

3.01 (1.62, 5.58)

 < 0.001

Cer(d18:1/16:0) as a categories variable (Quartiles)

 Cer(d18:1/16:0)

  Q1

Reference

 

  Q2

1.62 (1.16, 2.26)

0.005

1.62 (1.21, 2.36)

0.002

1.69 (1.14, 2.50)

 < 0.001

 Q3

2.74 (1.91, 3.92)

 < 0.001

2.84 (1.98, 4.07)

 < 0.001

2.97 (1.72, 5.11)

 < 0.001

  Q4

6.61 (4.23, 10.32)

 < 0.001

7.18 (4.62, 11.16)

 < 0.001

7.38 (3.02, 18.00)

 < 0.001

  P for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

  1. OR = Odds Ratio, CI = Confidence Interval.
  2. Model 1: adjusted for Male, Age;
  3. Model 2: adjusted for Male, Age, Hypertension, Diabete, Smoking;
  4. Model 3: adjusted for 12 Ceramide indices (Cer(d18:1/14:0), Cer(d18:1/18:0), Cer(d18:1/20:0), Cer(d18:1/22:0), Cer(d18:1/24:0), Cer(d18:1/24:1), Cer(d18:1/14:0)R, Cer(d18:1/16:0)R Cer(d18:1/18:0)R, Cer(d18:1/20:0)R, Cer(d18:1/22:0)R, Cer(d18:1/24:1)R).
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