Table 4 Univariate and multivariate analyses for the risk factors of IR in female with PCOS.

From: The association between serum growth differentiation factor 15 and insulin resistance in women diagnosed with polycystic ovary syndrome

Variables

OR(95%CI)

P value

OR(95%CI)

P value

Age

1.013(0.967,1.060)

0.589

  

BMI

1.087(1.019,1.159)

0.011

1.007(0.926,1.095)

0.867

Family members with diabetes

2.154(1.053,4.407)

0.036

1.732(0.720,4.170)

0.220

Family members with hypertension

0.889(0.481,1.640)

0.706

  

TG

3.159(1.735,5.751)

 < 0.001

1.201(0.522,2.760)

0.667

TC

1.047(0.760,1.443)

0.777

  

HDL-C

0.149(0.058,0.384)

 < 0.001

0.214(0.067,0.689)

0.010

LDL-C

1.165(0.822,1.651)

0.391

  

non-HDL-C

1.371(0.976,1.925)

0.069

1.157(0.709,1.889)

0.559

ALT

1.055(1.001,1.112)

0.046

1.036(0.972,1.104)

0.276

AST

1.035(0.973,1.101)

0.274

  

FSH

1.159(0.998,1.345)

0.053

1.051(0.854,1.295)

0.637

LH

1.074(1.020,1.132)

0.007

1.077(0.998,1.162)

0.053

LH/FSH

1.063(0.819,1.380)

0.645

  

PRL

1.043(1.004,1.085)

0.032

1.052(1.005,1.101)

0.030

E2

1.002(0.995,1.009)

0.570

  

TST

1.029(1.014,1.044)

 < 0.001

1.017(0.999,1.035)

0.059

GDF15

4.775(2.628,8.678)

 < 0.001

3.810(1.871,7.758)

 < 0.001

  1. BMI, body mass index; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; FSH, follicle stimulating-hormone; LH, luteinizing hormone; FPG, fasting plasma glucose; Fins, fasting insulin; HOMA-IR, homeostatic model assessment–insulin resistance; QUICKI, quantitative insulin-sensitivity check index; E2, Estradiol; TST, Testosterone; GDF15, growth differentiation factor 15. Log-transformed: GDF15.
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