Fig. 5

(A–C) Protein expression levels of SIRT1 and PGC-1α in lens epithelial cells. (D–H) Protein expression levels of MFN2, p-DRP1, NRF1 and TFAM in lens epithelial cells. (I) APPA regulates mitochondrial homeostasis through the SIRT1-PGC-1α signaling pathway (Created in BioRender). Data were presented as mean ± SD. *p < 0.05, **p < 0.01, and ***p < 0.001.