Fig. 2 | Scientific Reports

Fig. 2

From: Integrated multi-omics analysis and experimental verification reveal the involvement of the PI3K/Akt signaling pathway in myometrial fibrosis of adenomyosis

Fig. 2

Imaging and histological findings of AM. (A) Representative images of MRI for AM: The junctional zone is widened and blurred, the boundary between the deep and superficial muscle layers was unclear, the signal intensity was uneven, and scattered spot-like or round lipid-suppression hyperintense lesions are seen in the zone. From top to bottom are the Coronal, Axial, and Sagittal images. The circle indicates adenomyosis lesions. (B) Representative pictures of gross uterine specimen for AM. Above is the normal myometrium(NM) for control and the adenomyotic myometrium (AM) below. (C) Representative images of H&E staining in normal (top 2) and fibrotic adenomyotic myometrium (bottom 2). Arrows indicate endometrial glands and stroma. Scale bars, 400 μm and 100 μm, respectively. (D) Representative images of Masson trichrome staining in (top 2) and fibrotic adenomyotic myometrium (bottom 2). Scale bars, 200 μm and 100 μm, respectively.

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