Table 5 The top 10–20 genes with the highest total scores from the three algorithms (betweenness, closeness, and degree) identified as hub genes.
Hub genes from Gene set 2 | |||
Chek1 | Degree: 58.0 | Betweenness: 49.468735 | Closeness: 0.9142857 |
Exo1 | Degree: 58.0 | Betweenness: 47.324047 | Closeness: 0.9142857 |
Mcm2 | Degree: 46.0 | Betweenness: 58.157207 | Closeness: 0.7804878 |
Brca1 | Degree: 54.0 | Betweenness: 40.641666 | Closeness: 0.8648649 |
Atad5 | Degree: 48.0 | Betweenness: 29.220383 | Closeness: 0.8 |
RRM2 | Degree: 54.0 | Betweenness: 15.876 | Closeness: 0.8648649 |
Clspn | Degree: 52.0 | Betweenness: 14.249602 | Closeness: 0.84210527 |
Mcm5 | Degree: 52.0 | Betweenness: 11.436691 | Closeness: 0.84210527 |
Pole | Degree: 50.0 | Betweenness: 12.938581 | Closeness: 0.82051283 |
Mcm3 | Degree: 52.0 | Betweenness: 10.142668 | Closeness: 0.84210527 |
Hub genes from Gene set 3 | |||
Il1b | Degree: 270.0 | Betweenness: 49116.53 | Closeness: 0.4623568 |
Cd4 | Degree: 244.0 | Betweenness: 41852.504 | Closeness: 0.45711973 |
Cd44 | Degree: 198.0 | Betweenness: 24608.959 | Closeness: 0.4386646 |
Calml4 | Degree: 56.0 | Betweenness: 15920.103 | Closeness: 0.37817937 |
Mmp9 | Degree: 178.0 | Betweenness: 14974.843 | Closeness: 0.42227206 |
Nt5e | Degree: 96.0 | Betweenness: 14932.866 | Closeness: 0.39816773 |
Igf1 | Degree: 114.0 | Betweenness: 12931.386 | Closeness: 0.4100145 |
Anxa5 | Degree: 122.0 | Betweenness: 12428.538 | Closeness: 0.41061047 |
Fcna | Degree: 56.0 | Betweenness: 12406.415 | Closeness: 0.34221685 |
Cybb | Degree: 96.0 | Betweenness: 11763.509 | Closeness: 0.40213522 |
Pparg | Degree: 110.0 | Betweenness: 11240.115 | Closeness: 0.40647483 |
Cd36 | Degree: 124.0 | Betweenness: 11121.06 | Closeness: 0.4038599 |
Kit | Degree: 130.0 | Betweenness: 9614.034 | Closeness: 0.40912384 |
Fcgr4 | Degree: 88.0 | Betweenness: 9544.118 | Closeness: 0.38751715 |
Cd19 | Degree: 146.0 | Betweenness: 9220.762 | Closeness: 0.41271 |
Ccl5 | Degree: 142.0 | Betweenness: 8200.335 | Closeness: 0.4130117 |
Serpinb6a | Degree: 84.0 | Betweenness: 7866.1694 | Closeness: 0.38513973 |
Cd163 | Degree: 96.0 | Betweenness: 7612.835 | Closeness: 0.39788732 |
Col1a1 | Degree: 84.0 | Betweenness: 7386.8677 | Closeness: 0.37417218 |
Atp6v0d2 | Degree: 26.0 | Betweenness: 7068.5083 | Closeness: 0.34388313 |
Hub genes from Gene set 4 | |||
Ccnd1 | Degree: 46.0 | Betweenness: 6283.2686 | Closeness: 0.37789202 |
Pecam1 | Degree: 34.0 | Betweenness: 6285.1177 | Closeness: 0.36476427 |
Gp9 | Degree: 18.0 | Betweenness: 3217.905 | Closeness: 0.30184805 |
Zeb1 | Degree: 22.0 | Betweenness: 2763.5115 | Closeness: 0.35507247 |
Pbk | Degree: 34.0 | Betweenness: 2212.953 | Closeness: 0.3174946 |
Pik3r1 | Degree: 20.0 | Betweenness: 2176.1187 | Closeness: 0.32666665 |
Mcm7 | Degree: 44.0 | Betweenness: 1746.6061 | Closeness: 0.33409092 |
Selplg | Degree: 6.0 | Betweenness: 1692.0 | Closeness: 0.28107074 |
Ccr5 | Degree: 20.0 | Betweenness: 1668.0652 | Closeness: 0.3075314 |
Nop56 | Degree: 12.0 | Betweenness: 1639.3373 | Closeness: 0.27222222 |
Adgrl1 | Degree: 6.0 | Betweenness: 1597.8507 | Closeness: 0.23863636 |
Entpd1 | Degree: 18.0 | Betweenness: 1566.5822 | Closeness: 0.3056133 |
Jup | Degree: 14.0 | Betweenness: 1506.467 | Closeness: 0.32594234 |
Tmem119 | Degree: 6.0 | Betweenness: 1432.0 | Closeness: 0.22306526 |
Rpa2 | Degree: 34.0 | Betweenness: 1373.2267 | Closeness: 0.29166666 |
Cdk6 | Degree: 28.0 | Betweenness: 1315.469 | Closeness: 0.3325792 |
Ctbp2 | Degree: 10.0 | Betweenness: 1302.6005 | Closeness: 0.27579737 |
Ctps | Degree: 12.0 | Betweenness: 1159.8741 | Closeness: 0.28 |
Rtn4rl1 | Degree: 4.0 | Betweenness: 1144.0 | Closeness: 0.1949602 |
Brca2 | Degree: 30.0 | Betweenness: 1049.0101 | Closeness: 0.32166302 |
