Fig. 5

E. faecalis SI-FC-01 can enhance the stress resistance of C. elegans via AKT signaling pathway. a The changes in lifespan of wild type worms N2 treated with E. faecalis SI-FC-01 after heat stress at 35°C (N = 90 worms, two-way ANOVA). The changes in lifespan of N2 (b), TJ1052 age-1(hx546) (c), GR1310 akt-1(MG144) (d), VC204 akt-2(ok393) (e), CF1038 daf-16(mu86) (f) treated with E. faecalis SI-FC-01 after H2O2 oxidative stress (N = 90 worms, two-way ANOVA). (g) Relative expression of daf-16 downstream genes in 8-day-old worms (N2) treated with E. faecalis SI-FC-01 (Student’s t-test).