Table 1 The reported analytical methods for the detection of DOX.

From: Spectrophotometric and smartphone-based colorimetric methods utilizing polyvinylpyrrolidone-capped silver nanoparticles for determining doxorubicin in human plasma samples

Composite

Method

Linear range

LOD/LLOQ

Sample

References

Nafion composite

Electrochemical

5–2000 nM

1 nM

Plasma

48

GQD

Electrochemical

0.018–3.60 µM

0.016 µM

Plasma

49

MWNTs

Electrochemical

0.0025–0.25 µM

1.0 nM

Whole blood

50

MWCNTs

Electrochemical

0.04–90 µM

0.0094 µM

Serum, urine

51

CoFe2O4/MNPs

Electrochemical

0.05–1150 nM

10 pM

Serum, urine

52

MWCNTs/Pt

Electrochemical

0.05–4.0 µM

0.002 µg/mL

Plasma

53

Fe3O4-GO-SO3H

Electrochemical

0.043–3.5 µM

0.026–3.5 µM

0.86–13.0 µM

0.0049 µM

0.0043 µM

0.014 µM

Plasma

Urine

CF

11

Poly arginine

Electrochemical

0.069–1.08

LLOQ: 0.069 nM

Plasma

11

Polytoluidine blue

Electrochemical

340–8.6

LLOQ: 0.34 nM

Plasma

14

Ag nanoplates

Spectrophotometric smartphone

0.25–5.0 µg/mL

0.5–5.0 µg/mL

0.5 µg/mL

0.25 µg/mL

Plasma

This work