Table 2 Comparison of clinical features in patients with de novo Parkinson’s disease with or without mild cognitive impairment.

From: Association between cognitive and autonomic dysfunctions in patients with de novo Parkinson’s disease

Variable

MCI (n = 21)

Non-MCI (n = 61)

P value

Age, yr

71.05 ± 8.67

70.05 ± 9.57

0.6604

Gender-female

10 (47.62%)

36 (59.02%)

0.4472

Level of education, yr

10.26 ± 4.55

9.41 ± 5.04

0.476

Disease duration, yr

1.50 ± 1.04

1.35 ± 0.94

0.5749

UPDRS-Part III (motor)

25.00 ± 13.51

23.51 ± 10.72

0.6497

The HY stage

2 [2 – 2.5]

2 [2–2]

0.416

SCOPA-AUT

 Gastrointestinal score

4 [1–7]

1 [0–4]

0.0319

 Urinary score

9 [6–10]

5 [3–10]

0.092

 Cardiovascular score

0 [0–1]

0 [0–1]

0.285

 Thermoregulatory score

1 [0–2]

0 [0–1]

0.0695

 Pupillomotor score

0 [0–1]

0 [0–0]

0.3252

 Total dysautonomia score*

15.86 ± 8.03

10.72 ± 7.93

0.016

  1. Numerical data are presented as mean ± SD for normal distribution or otherwise median (interquartile range) after conducting test of normality with Kolmogorov–Smirnov test. Non-numerical data are shown as number (%).
  2. *Total score of SCOPA-AUT was calculated except for sexual domain, since only 25 patients answered the question for the sexual dysfunction.
  3. UPDRS, Unified Parkinson Disease Rating Scale; HY, Hoehn and Yahr; SCOPA-AUT, Scales for Outcomes in Parkinson’s disease – Autonomic.
  4. Significant values are in bold.
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