Table 4 Overview of transcriptional factor (TF) biomolecules of differentially expressed genes of tuberculosis.
TF name | Description | Function |
|---|---|---|
FOXC1 | Forkhead box C1 | Transcription factor activity that binds DNA and transcription factor binding |
HOXA5 | Homeobox A5 | Transcription factor activity that binds DNA and RNA polymerase II |
PPARG | Peroxisome proliferator-activated receptor gamma | Transcription factor activity that binds DNA and chromatin linking |
USF2 | Upstream transcription Factor 2, C-Fos interacting | Transcription factor activity that binds DNA and sequence-specific DNA binding |
JUN | Jun proto-oncogene, AP-1 transcription factor subunit | RNA binding and sequence-specific DNA binding |
E2F1 | E2F transcription factor 1 | Transcription factor activity that binds DNA and transcription factor binding |
NFKB1 | Nuclear factor kappa B subunit 1 | Transcription factor activity that binds DNA and sequence-specific DNA binding |
GATA2 | GATA binding protein 2 | Transcription factor activity that binds DNA and chromatin binding |
YY1 | YY1 transcription factor | Transcription factor activity that binds DNA and transcription coactivator activity |
RUNX1 | RUNX family transcription factor 1 | Transcription factor activity that binds DNA and protein homodimerization activity |
FOXP1 | Forkhead box P1 | Transcription factor activity that binds DNA and sequence-specific DNA binding |
HNF4A | Hepatocyte nuclear factor 4 alpha | Transcription factor activity that binds DNA and sequence-specific DNA binding |
REST | RE1 silencing transcription factor | Transcription factor activity that binds DNA and transcription factor binding |
TP53 | Tumor protein P53 | Transcription factor activity that binds DNA and protein heterodimerization activity |
FLI1 | Fli-1 proto-oncogene, ETS transcription factor | Transcription factor activity that binds DNA and chromatin binding |
MYC | MYC proto-oncogene, BHLH transcription factor | Transcription factor activity that binds DNA and RNA polymerase II cis-regulatory region sequence-specific DNA binding |
KLF4 | KLF transcription factor 4 | Transcription factor activity that binds DNA and transcription factor binding |
STAT3 | Signal transducer and activator of transcription 3 | Transcription factor activity that binds DNA and sequence-specific DNA binding |
CREM | CAMP responsive element modulator | Transcription factor activity that binds DNA and core promoter sequence-specific DNA binding |
SOX2 | SRY-Box transcription factor 2 | Transcription factor activity that binds DNA and protein heterodimerization activity |
NANOG | Nanog homeobox | Transcription factor activity that binds DNA and chromatin binding |
SPI1 | Spi-1 proto-oncogene | Transcription factor activity that binds DNA and RNA binding |
POU5F1 | POU class 5 homeobox 1 | RNA binding and DNA binding particular to certain sequences |
