Table 1 Comparison of clinical and hormonal parameters between patients with and without follicle growth in 165 patients with primary ovarian insufficiency (POI).

From: A highly sensitive Anti-Müllerian hormone test as a promising tool for follicle growth prediction in primary ovarian insufficiency patients

Clinical parameters

Total (n = 165)

Without follicle growth (n = 124)

Follicle growth (n = 41)

P-valuea

Female age (years)

36 (32, 41)

36 (32, 41)

38 (33, 41)

0.133b

Presumed age of POI onset (years)

30 (24, 37)

29 (23, 35)

34 (27, 38)

0.004b

Duration of amenorrhea (years)

5 (3, 9.75)

6.5 (3, 11)

4 (2, 6)

0.003b

BMI (kg/m2)

20.67 (19.15, 22.57)

20.59 (19.15, 22.36)

21.34 (20.03, 22.94)

0.048b

Baseline LH (mIU/mL)

33.1 (23.2, 43.3)

33.35 (22.25, 43.3)

30.6 (21.3, 36)

0.065b

Baseline FSH (mIU/mL)

78.1 (60.32, 102.45)

84.8 (60.60, 109.68)

73.7 (50.2, 98.7)

0.045b

Baseline ultrasound-detectable follicle number

0 (0, 0.75)

0 (0, 0)

0 (0, 1)

0.018b

Clinical pregnancy history

17/163 (10.43%)

11/123 (8.94%)

6/40 (15%)

0.21c

Chromosomal abnormality

15/148 (10.14%)

10/112 (8.93%)

5/36 (13.89%)

0.284c

Elevated serum autoantibody

66/160 (41.25%)

52/119 (43.7%)

14/41 (34.15%)

0.188c

  1. BMI, body mass index; LH, luteinizing hormone; FSH, follicle-stimulating hormone.
  2. Values for continuous variables are presented as median (25th, 75th percentile), and categorical variables as frequency and percentage (n/N, %).
  3. aCompare without follicle growth and follicle growth groups.
  4. bMann–Whitney U test.
  5. cFisher exact test.
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