Fig. 6 | Scientific Reports

Fig. 6

From: Integrated spatial and single cell transcriptomics identifies PRKDC as a dual prognostic biomarker and therapeutic target in hepatocellular carcinoma

Fig. 6

Correlation between PRKDC expression and clinical survival and diagnosis. (A) Kaplan-Meier survival curve for overall survival in HCC patients stratified by PRKDC expression. (B) Kaplan-Meier survival curve stratified by expression grade in HCC. (C) Chi-square test was performed on the number of survival and death samples at different expression levels. (D) A meta-analysis of Univariate Cox survival analysis on multiple datasets. (E) Independent prognostic analysis to show whether the gene’s association with tumor survival is independent of traditional clinical variables. (F) Kaplan-Meier survival curve comparing overall survival in HCC patients with high or low PRKDC expression combined with stroma. (G) Kaplan-Meier survival curve comparing overall survival in HCC patients stratified by PRKDC expression and tumor microenvironment. (H) Kaplan-Meier survival curve comparing overall survival in HCC patients stratified by PRKDC expression and immune.

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