Table 1 Potential molecular compounds associated with the six HIRI-related hub genes.

From: Identification of PANoptosis related biomarkers to predict hepatic ischemia‒reperfusion injury after liver transplantation

Gene

Inference network

Inference score

Reference count

HSPA1A

4-phenylbutyric acid, Acetylcysteine, Antimycin A, Blood Glucose, cobaltous chloride, Cocaine, Cyclosporine, Deferoxamine, Dexamethasone, Edaravone, Estradiol, Ethanol, Hydrogen Peroxide, Indomethacin, Morphine, Oxygen, pirinixic acid, Quercetin, Ranitidine, Reactive Oxygen Species, Resveratrol, Rotenone, sodium arsenite, tert-Butylhydroperoxide, Troglitazone

55.59

79

HSPA1B

Acetylcysteine, alpha-Tocopherol, Antimycin A, Blood Glucose, cinnamaldehyde, cobaltous chloride, Cocaine, Cyclosporine, Dexamethasone, Estradiol, Ethanol, Hydrogen Peroxide, Oxygen, pirinixic acid, Quercetin, Resveratrol, Rotenone, Sirolimus, sodium arsenite, tert-Butylhydroperoxide

46.51

66

IRF1

15-deoxy-delta(12,14)-prostaglandin J2, Acetylcysteine, Antimycin A, Cyclosporine, Dexamethasone, Estradiol, Ethanol, Flutamide, Glucose, Hydrogen Sulfide, mangiferin, pirinixic acid, Reactive Oxygen Species, Resveratrol, Rosiglitazone, Simvastatin, sodium arsenite, Streptozocin, tert-Butylhydroperoxide, Troglitazone

51.71

51

TNFAIP3

Acetylcysteine, Adenosine, Antimycin A, bardoxolone methyl, Cyclosporine, Dexamethasone, Dihydrotestosterone, Estradiol, Ethanol, Gallic Acid, Hydrogen Peroxide, Mannitol, Oxygen, pirinixic acid, Quercetin, Resveratrol, Rotenone, sodium arsenite, tert-Butylhydroperoxide, Testosterone, Troglitazone

49.37

63

CEBPB

4-phenylbutyric acid, Acetylcysteine, Antimycin A, baicalein, Capsaicin, cobaltous chloride, Cyclosporine, Dexamethasone, Epinephrine, Estradiol, Ethanol, Gallic Acid, Glucose, Hydrogen Peroxide, Indomethacin, Mifepristone, Nicotine, Nitroprusside, Oxygen, pirinixic acid, Quercetin, Reactive Oxygen Species, Resveratrol, Rosiglitazone, Rotenone, Sevoflurane, sodium arsenite, Streptozocin, Telmisartan, tert-Butylhydroperoxide, Testosterone, Troglitazone, Vitamin D

78.54

84

SERPINE1

15-deoxy-delta(12,14)-prostaglandin J2, Blood Glucose, Capsaicin, cinnamaldehyde, cobaltous chloride, Cyclosporine, Dexamethasone, Dihydrotestosterone, Epinephrine, Estradiol, Fenofibrate, Flutamide, Glucose, Heparin, Hydrogen Peroxide, Hydrogen Sulfide, Indomethacin, Losartan, mangiferin, Mifepristone, Morphine, Nicotine, notoginsenoside R1, N-(oxo-5,6-dihydrophenanthridin-2-yl)-N, N-dimethylacetamide hydrochloride, Oxygen, Pentoxifylline, pirinixic acid, Quercetin, Ranitidine, Resveratrol, Rosiglitazone, Rotenone, Simvastatin, Sirolimus, sodium arsenite, Streptozocin, Superoxides, Tacrolimus, Telmisartan, tert-Butylhydroperoxide, Testosterone, Troglitazone, Vitamin D

98.93

93

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