Fig. 10 | Scientific Reports

Fig. 10

From: Unveiling the role of Ndrg1 gene on the oxidative stress induction behind the anticancer potential of styrylquinazoline derivatives

Fig. 10

The toxicity of IS20 in Danio rerio experimental model. (A) Toxicity (expressed as LC50) after 24, 48 and 72 h of incubation with IS20; (B) Toxicity (expressed as LC50) of IS20 in FET after 96 h of incubation; (C) Cardiotoxicity, measured as heart rate [beats per minute], the statistical analysis of the data was performed using a one-way ANOVA with Tukey’s post-hoc test: *p < 0.05 compared to the untreated control (E3) fish; (D) Example of malformations stated for the incubation with IS20 versus untreated control (E3) fish; PE pericardial edema, TA tail autophagy.

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