Table 2 Comparison on the toxic effects of the same concentration of the compounds in the insect larvae of G. mellonella and human fibroblast cell lines.
From: Galleria mellonella as a drug discovery model to study oxidative stress
Compound | Concentration/µM | % Survival in larvae | % Cell viability in human fibroblast cells |
|---|---|---|---|
Resveratrol | 219.1 | 100 | 44.8 |
Indole-3-propionic acid | 798.2 | 100 | 52.9 |
Trolox | 599.3 | 100 | 96.9 |
Alpha tocopherol | 580.4 | 100 | 110 |
Alpha lipoic acid | 242.3 | 100 | 96.9 |
Ginsenoside RB1 | 45.1 | 100 | 64.6 |
Orotic acid | 960.9 | 100 | 40.2 |
Xanthohumol | 14.1 | 100 | 74.9 |