Table 2 Comparison on the toxic effects of the same concentration of the compounds in the insect larvae of G. mellonella and human fibroblast cell lines.

From: Galleria mellonella as a drug discovery model to study oxidative stress

Compound

Concentration/µM

% Survival in larvae

% Cell viability in human fibroblast cells

Resveratrol

219.1

100

44.8

Indole-3-propionic acid

798.2

100

52.9

Trolox

599.3

100

96.9

Alpha tocopherol

580.4

100

110

Alpha lipoic acid

242.3

100

96.9

Ginsenoside RB1

45.1

100

64.6

Orotic acid

960.9

100

40.2

Xanthohumol

14.1

100

74.9

  1. Results represent the treatment of the larvae and cell lines for 48 h.