Table 2 Unadjusted association between baseline variables and hospital mortality.
From: A U shaped association between the HCT-ALB and hospital mortality in patients with sepsis
Exposure | Statistics | Hospital mortality | P value |
|---|---|---|---|
HR (95% CI) | |||
Age (year) | 65.933 ± 15.540 | 1.020 (1.016, 1.023) | < 0.00001 |
Sex | |||
Male | 3964 (52.538%) | Reference | |
Female | 3581 (47.462%) | 1.035 (0.939, 1.139) | 0.49048 |
BMI (kg/m2) | 27.38 (23.08–33.27) | 1.000 (1.000, 1.000) | 0.14564 |
Ethnicity | |||
Caucasian | 5819 (77.607%) | Reference | |
African American | 703 (9.376%) | 0.820 (0.692, 0.971) | 0.02135 |
Hispanic | 342 (4.561%) | 0.850 (0.668, 1.081) | 0.18409 |
Asian | 120 (1.600%) | 1.096 (0.763, 1.574) | 0.62081 |
Native American | 112 (1.494%) | 1.117 (0.752, 1.659) | 0.58532 |
Other/unknown | 402 (5.361%) | 0.818 (0.652, 1.027) | 0.08306 |
Temperature (°C) | 36.473 ± 1.307 | 0.857 (0.835, 0.881) | < 0.00001 |
Heart rate (/min) | 112.549 ± 30.034 | 1.004 (1.003, 1.006) | < 0.00001 |
Mean BP (mmHg) | 54.00(45.00-98.75) | 0.999 (0.997, 1.000) | 0.00911 |
WBC (109/L) | 14.10(8.10–21.20) | 1.009 (1.006, 1.013) | < 0.00001 |
HCT-ALB | 6.316 ± 7.534 | 1.025 (1.019, 1.032) | < 0.00001 |
HCT-ALB tertile | |||
Tertile 1 | 2483 (32.905%) | Reference | |
Tertile 2 | 2542 (33.687%) | 0.966 (0.851, 1.096) | 0.59098 |
Tertile 3 | 2521 (33.408%) | 1.405 (1.251, 1.577) | < 0.00001 |
Site of infection | |||
Pulmonary | 2598 (34.429%) | Reference | |
Renal/UTI | 1694 (22.449%) | 0.727 (0.629, 0.840) | 0.00001 |
GI | 1223 (16.207%) | 0.979 (0.853, 1.122) | 0.75775 |
Unknown | 957 (12.682%) | 1.124 (0.970, 1.303) | 0.12102 |
Cutaneous/soft tissue | 561 (7.434%) | 0.580 (0.465, 0.723) | < 0.00001 |
Other | 513 (6.798%) | 0.823 (0.677, 1.000) | 0.05028 |
AIDS | |||
No | 7521 (99.669%) | Reference | |
Yes | 25 (0.331%) | 1.052 (0.472, 2.346) | 0.9006 |
Metastatic cancer | |||
No | 7261 (96.223%) | Reference | |
Yes | 285 (3.777%) | 2.038 (1.674, 2.482) | < 0.00001 |
Diabetes | |||
No | 5553 (73.589%) | Reference | |
Yes | 1993 (26.411%) | 0.840 (0.750, 0.941) | 0.00268 |
CHF | |||
No | 6940 (91.969%) | Reference | |
Yes | 606 (8.031%) | 1.148 (0.974, 1.354) | 0.09938 |
AMI | |||
No | 7293 (96.647%) | Reference | |
Yes | 253 (3.353%) | 0.954 (0.729, 1.248) | 0.72997 |
Pneumonia | |||
No | 5326 (70.580%) | Reference | |
Yes | 2220 (29.420%) | 1.020 (0.919, 1.132) | 0.70784 |
Arrhythmia | |||
No | 6261 (82.971%) | Reference | |
Yes | 1285 (17.029%) | 1.115 (0.991, 1.255) | 0.07008 |
Vasopressor use | |||
No | 7402 (98.092%) | Reference | |
Yes | 144 (1.908%) | 1.826 (1.396, 2.389) | 0.00001 |
Ventilation | |||
No | 5239 (69.428%) | Reference | |
Yes | 2307 (30.572%) | 1.713 (1.555, 1.888) | < 0.00001 |
Dialysis | |||
No | 6935 (91.903%) | Reference | |
Yes | 611 (8.097%) | 0.866 (0.724, 1.034) | 0.11232 |
SOFA score | 4.956 ± 2.392 | 1.141 (1.121, 1.160) | < 0.00001 |
Acute physiology score III | 68.137 ± 25.449 | 1.023 (1.021, 1.024) | < 0.00001 |
Apache IV score | 82.194 ± 26.513 | 1.024 (1.022, 1.026) | < 0.00001 |
GCS score | 12.179 ± 3.660 | 0.925 (0.914, 0.935) | < 0.00001 |
