Table 5 Stratified association between HCT-ALB and hospital mortality by age, sex, BMI, ventilation, diabetes, CHF, pneumonia and arrhythmia.
From: A U shaped association between the HCT-ALB and hospital mortality in patients with sepsis
Subgroup | N | Unadjusted HR (95%CI) | P value | Adjusted HR (95%CI) | P value | P for interaction |
|---|---|---|---|---|---|---|
Age (year) | 0.0059 | |||||
< 65 | 3274 | 1.000 (0.990, 1.010) | 0.9968 | 1.006 (0.995, 1.017) | 0.2676 | |
≥ 65 | 4272 | 1.025 (1.017, 1.033) | < 0.0001 | 1.022 (1.014, 1.031) | < 0.0001 | |
Sex | 0.8171 | |||||
Male | 3964 | 1.012 (1.003, 1.021) | 0.008 | 1.014 (1.004, 1.023) | 0.0037 | |
Female | 3581 | 1.019 (1.009, 1.028) | 0.0001 | 1.017 (1.007, 1.028) | 0.0009 | |
BMI (kg/m2) | 0.2963 | |||||
Underweight | 382 | 1.041 (1.013, 1.070) | 0.004 | 1.037 (1.006, 1.070) | 0.0196 | |
Normalweight | 2264 | 1.013 (1.002, 1.025) | 0.0255 | 1.014 (1.001, 1.026) | 0.0305 | |
Overweight | 1972 | 1.017 (1.004, 1.030) | 0.0082 | 1.023 (1.009, 1.036) | 0.0008 | |
Obese | 2701 | 1.009 (0.998, 1.020) | 0.1066 | 1.011 (0.999, 1.023) | 0.0668 | |
Ventilation | 0.4417 | |||||
No | 5239 | 1.020 (1.011, 1.029) | < 0.0001 | 1.016 (1.006, 1.025) | 0.0014 | |
Yes | 2307 | 1.006 (0.997, 1.015) | 0.2258 | 1.011 (1.001, 1.021) | 0.0289 | |
Diabetes | 0.6736 | |||||
No | 5553 | 1.015 (1.007, 1.022) | < 0.0001 | 1.016 (1.008, 1.024) | < 0.0001 | |
Yes | 1993 | 1.012 (0.999, 1.025) | 0.0782 | 1.020 (1.005, 1.034) | 0.0076 | |
CHF | 0.2703 | |||||
No | 6940 | 1.013 (1.006, 1.020) | 0.0002 | 1.013 (1.006, 1.021) | 0.0002 | |
Yes | 606 | 1.030 (1.010, 1.051) | 0.0036 | 1.038 (1.013, 1.063) | 0.0025 | |
Pneumonia | 0.312 | |||||
No | 5326 | 1.017 (1.009, 1.025) | < 0.0001 | 1.015 (1.007, 1.024) | 0.0004 | |
Yes | 2220 | 1.013 (1.002, 1.025) | 0.0211 | 1.019 (1.007, 1.031) | 0.0026 | |
Arrhythmia | 0.1468 | |||||
No | 6261 | 1.015 (1.008, 1.023) | < 0.0001 | 1.016 (1.009, 1.024) | < 0.0001 | |
Yes | 1285 | 1.011 (0.998, 1.025) | 0.1029 | 1.019 (1.004, 1.034) | 0.0152 |
