Table 2 Diagnostic performance of radiomic model, clinical model, and three radiologists for predicting the differentiation grade of INMA.

From: CT radiomics from intratumor and peritumor regions for predicting poorly differentiated invasive nonmucinous pulmonary adenocarcinoma

 

AUC (95%CI)

Accuracy (95%CI)

Specificity (95%CI)

Sensitivity (95%CI)

Internal test cohort

 The clinical model

0.875 (0.811–0.938)

0.766 (0.682–0.837)

0.753 (0.650–0.838)

0.800 (0.631–0.916)

 The intratumor radiomic model

0.882 (0.807–0.957)

0.839 (0.759–0.896)

0.876 (0.786–0.934)

0.743 (0.564–0.868)

 The combined_3mm radiomic model

0.907 (0.844–0.969)

0.855 (0.778–0.909)

0.876 (0.786–0.934)

0.800 (0.625–0.909)

 The combined_5mm radiomic model

0.858 (0.783–0.933)

0.790 (0.706–0.856)

0.831 (0.734-0.900)

0.686 (0.506–0.826)

Without AI assistance

 Junior radiologist 1

0.666 (0.558–0.773)

0.669 (0.579–0.751)

0.674 (0.567–0.770)

0.657 (0.478–0.809)

 Junior radiologist 2

0.694 (0.588-0.800)

0.710 (0.621–0.788)

0.730 (0.626–0.819)

0.657 (0.478–0.809)

 Senior radiologist 3

0.765 (0.671–0.859)

0.750 (0.664–0.823)

0.730 (0.626–0.819)

0.800 (0.631–0.916)

With AI assistance

 Junior radiologist 1

0.821 (0.733–0.910)*

0.831 (0.753–0.892)

0.843 (0.750–0.911)

0.800 (0.631–0.916)

 Junior radiologist 2

0.827 (0.739–0.915)*

0.839 (0.762–0.899)

0.854 (0.763–0.920)

0.800 (0.631–0.916)

 Senior radiologist 3

0.850 (0.770–0.930)*

0.847 (0.771–0.905)

0.843 (0.750–0.911)

0.857 (0.697–0.952)

External test cohort

 The clinical model

0.760 (0.603–0.916)

0.737 (0.569–0.866)

0.692 (0.482–0.857)

0.833 (0.516–0.979)

 The intratumor radiomic model

0.760 (0.580–0.939)

0.789 (0.622–0.899)

0.923 (0.734–0.987)

0.500 (0.223–0.777)

 The combined_3mm radiomic model

0.772 (0.593–0.952)

0.816 (0.651–0.917)

0.961 (0.784–0.998)

0.500 (0.223–0.777)

 The combined_5mm radiomic model

0.766 (0.593–0.952)

0.763 (0.594–0.880)

0.885 (0.687–0.970)

0.500 (0.223–0.777)

  1. *Referring to P < 0.05. Radiologists of all seniorities were more advanced in diagnosis with the assistance of the AI model.