Fig. 6
Transcriptome analysis of F1 larvae at 96 hpf from maternal zebrafish with T2DM. (a) Volcano Plot of differentially expressed genes (DEGs). Upregulated genes shown in red, downregulated genes in green. (b) Gene Ontology (GO) Enrichment Analysis of DEGs. Biological processes shown in red, cellular components shown in blue, molecular functions shown in green. (c) Kyoto Encyclopedia of Genes and Genomes (KEGG)61 enrichment analysis of DEGs. The highlighted signalling pathways are related to lipid and glucose metabolism. (d) Protein-protein interactive (PPIN) of DEGs. The size and colour intensity represent the degree (number of interactions), n = 4 biological replicates per group.
