Table 3 The linkage between serum mBDNF and NPZ-6 trajectory groups presented by conditional and joint probabilities from the group-based dual trajectory model.

From: Dual trajectories of serum brain-derived neurotrophic factor and cognitive function in people living with HIV

NPZ-6 trajectory group

Serum mBDNF trajectory group

Low baseline-Slow improvement

Gradual improvement

Late surge

Total

3a Probability of NPZ-6 group conditional on serum mBDNF group

 Peak with gradual decline

0.32

0.68

0

1

 Stable ascent

0.22

0.68

0.10

1

3b Probability of Serum mBDNF group conditional on NPZ-6 trajectory group

 Peak with gradual decline

0.22

0.17

0

 

 Stable ascent

0.78

0.83

1

 

 Total

1

1

1

 

3c Joint probability of Serum mBDNF and NPZ-6 trajectory groups

 Peak with gradual decline

0.05

0.11

0.00

 

 Stable ascent

0.19

0.56

0.08

 
  1. 3a, Conditional probability of an individual being in a specific NPZ-6 cognitive trajectory given their serum mBDNF trajectory group. 3b, the probability of an individual belonging to a specific serum mBDNF trajectory group given their NPZ-6 cognitive trajectory; 3c, the joint probabilities, combining the two aspects (serum mBDNF trajectory and NPZ-6 cognitive trajectory) to indicate the probability of both occurring together.
  2. Abbreviations: mBDNF, mature Brain-derived Neurotrophic Factor; NPZ-6, Composite cognitive score derived from individual cognitive tests.
  3. Values in bold represent high conditional and joint probabilities.
Back to article page