Fig. 1 | Scientific Reports

Fig. 1

From: Lifetime existence of a core of mutualistic symbionts and functionally uncoupled taxa in the gut of a Mediterranean cohort

Fig. 1

Multi-omics of fecal samples in the IAE cohort study. (a) Thirty healthy participants from the Valencian Region (Spain), with an age distribution spanning groups I, A, and E, were recruited to characterize microbiome communities throughout life using 16S, MG, and MT. (b) A long-term survey was conducted in which up to eight fecal samples per individual were attempted to be collected. This yielded 219 MG and 116 MT, which, after quality control, resulted in 218 16S rRNA gene amplicons, 156 whole-genome shotgun MG, and 79 MT. (c) PCoA with Bray–Curtis dissimilarities for all samples based on 16S rRNA gene taxonomy (above from left to right, ASVs and genus levels, respectively) and functions (bottom from left to right, MG, and MT, respectively). (d) Summary of the nested Permanovas, where the g, t, and i interactions were estimated for taxonomy and functions. DOF indicates degrees of freedom, and R2(%) represents the percentage of explained variance by each factor and interaction. Stars correspond to the statistical significance of the tests.

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