Fig. 1

Interactive combined effects of baseline levels of serum interleukin-1 beta (sIL-1β) and the Neuroticism of the big five inventory on the probability of 12-week remission. ^aInteractive effects of sIL-1β and Neuroticism on remission status were estimated using multinomial logistic regression; and ^bodds ratios (95% confidence intervals) [OR (95% CI) were calculated using binary logistic regression for lower (< 1.11 pg/mL) vs. higher (≥ 1.11 pg/mL) sIL-1β levels on remission status, after adjustment for age, marital status, monthly income, atypical feature, number of depressive episodes, duration of present illness, number of physical disorders, scores on Hospital anxiety & depression scale-anxiety subscale and alcohol use disorder identification test, and treatment steps. ^*P < 0.05; ^‡P < 0.001.