Table 1 Children’s characteristics stratified by early (time to DC ≤ 2 h) and late DC (> 2 h) after hospital admission for severe traumatic brain injury in Germany, 2016–2022.

From: Timing of decompressive craniectomy and short-term outcomes in pediatric severe traumatic brain injury: a nationwide observational study in Germany

 

Total (N = 589),

No.(%)

Early DC (n = 323),

No.(%)

Late DC (n = 266),

No. (%)

Age, median (IQR)

12 (4–16)

12 (3–16)

11 (5–16)

Age categories

   

0–5

171 (29.0)

96 (29.7)

75 (28.2)

6–12

121 (20.5)

60 (18.6)

61 (22.9)

13–17

297 (50.4)

167 (51.7)

130 (48.9)

Sex, male

395 (67.1)

220 (68.1)

175 (65.8)

LOS in days, median (IQR)

17 (5–29)

11 (2–23)

21.5 (9–32)

LOS in survivors, median (IQR)**

22 (13–35)

19 (11–33)

24 (16–35)

Transferred cases

50 (8.4)

27 (8.3)

23 (8.6)

In-hospital mortality

163 (27.7)

121 (37.5)

42 (15.8)

14-days In-hospital mortality,

155 (26.3)

116 (35.9)

39 (14.7)

Time to death after DC,

median (IQR)

2 (1–6)

2 (1–4)

4 (1–5)

Mechanical ventilation (days),

median (IQR)**

7.5 (2.5–15.8)

5 (1.7–12)

10.8 (5.9–19)

Serious extracranial injuries (AIS ≥ 3)

Thorax

195 (33.1)

118 (36.5)

77 (28.9)

Abdomen

28 (4.7)

21 (6.5)

7(2.6)

Spine

11 (1.9)

6 (1.9)

5 (1.8)

Type of head injury

EH (Epidural)

166 (28.2)

92 (28.5)

74 (27.8)

SH (Subdural)

411 (69.8)

231 (71.5)

180 (67.7)

SAH (Subarachnoid)

223 (37.9)

116 (35.9)

107 (40.2)

Brain oedema

382 (64.8)

210 (65.0)

172 (64.7)

Complications

IHCA

67 (11.4)

35 (10.8)

32 (12.0)

OHCA

20 (3.4)

11 (3.4)

9 (3.4)

Coma

184 (31.2)

112 (34.7)

72 (27.1)

Seizure

73 (12.4)

34 (10.5)

39 (14.7)

Epilepsy

18 (3.0)

5 (1.5)

13 (4.9)

DIC

30 (5.0)

24 (7.4)

6 (2.3)

PCCC in survivors, median (IQR)**

2 (1–3)

2 (1–2)

2 (0–3)

Evacuation of hematoma

373 (63.3)

233 (72.1)

140 (52.6)

EVD

126 (21.4)

56 (17.3)

70 (26.3)

Preoperative

xx

xx

41/70 (58.6)

Intraoperative

48 (38.1)

32/56 (57.1)

16/70 (22.8)

Postoperative

xx

xx

13/70 (18.6)

Time to EVD (days), median (IQR)

3.5 (1–47)

2 (1-29.5)

13 (1–73)

ICP monitoring

307 (52.1)

153 (47.4)

154 (57.9)

Preoperative

127 (41.3)

7/153 (4.5)

120/154 (77.9)

Intraoperative

159 (51.8)

132/153 (86.3)

27/154 (17.5)

Postoperative

21 (6.8)

14/153 (9.2)

7/154 (4.6)

Time to ICP (minutes), median (IQR)

84 (52–149)

67 (38–105)

120 (65–428)

Tracheostomy **

117 (27.5)

43(21.3)

74(33.0)

Gastrostomy**

68(15.9)

28(13.9)

40(19.8)

POFI, median (IQR)

0 (0–0)

0 (0–0)

0 (0–0)

ISS, median (IQR)

13 (9–22)

13 (9–22)

13 (9–19)

Single ICISS, median (IQR)

0.67(0.56–0.77)

0.62 (0.50–0.77)

0.68 (0.56–0.77)

Multiple ICISS, median (IQR)

0.11(0.02–0.32)

0.11 (0.02–0.31)

0.13 (0.03–0.34)

  1. DC Decompressive craniectomy, LOS length of stay, IHCA Intrahospital cardiac arrest, OHCA Out of hospital cardiac arrest, DIC Disseminated intravascular coagulation, PCCC Pediatric Complex Chronic Conditions, EVD Extra ventricular drain, ICP Intracranial pressure, POFI Postoperative Organ Failure Index, ISS Injury Severity Score, ICISS International Classification Injury Severity Score, IQR Interquartile range, xx Censored data, NA not available.**Survivors of DC (n = 426).