Fig. 2
From: A repurposing Dapagliflozin via polymeric nanogels for colorectal cancer therapy
Powder X-ray diffraction (PXRD) patterns of Dapagliflozin (DAPA), Polyvinyl Alcohol (PVA), Sodium Alginate (SA), physical mixture of DAPA-PVA-SA, optimum DAPA-PVA-SA nanoparticles, and blank PVA-SA nanoparticles. The sharp diffraction peaks of pure DAPA indicate its crystalline nature, while the broad patterns of polymers (PVA, SA) suggest amorphous characteristics. The disappearance of DAPA’s crystalline peaks in the nanoparticle formulations confirms successful encapsulation and transformation into an amorphous form, enhancing solubility and bioavailability.
