Table 4 Statistical comparison of cervical microbiota using Kruskal–Wallis Test.

From: Cell cycle gene expression and microbial profiles associated with HPV related cervical neoplasia and cervical microbiome shifts

Taxonomy

HPV-16

HPV-18

Not-infection

Squared

p-value

N

%

N

%

N

%

Genus

Lactobacillus

49,335

23.19%

173,253

66.92%

61,394

34.52%

20

0.4579

Gardnerella

124

0.06%

7160

2.77%

45,256

25.45%

17.321

0.185

Prevotella_7

23,472

11.03%

90

0.03%

0

0.00%

5.0893

0.4051

Stenotrophomonas

46,030

21.64%

22,671

8.76%

21,124

11.88%

20

0.4579

Corynebacterium

14,391

6.77%

2410

0.93%

620

0.35%

16.837

0.2069

Delftia

27,787

13.06%

12,319

4.76%

8631

4.85%

20

0.3946

Bacillus

15,079

7.09%

11,162

4.31%

14,083

7.92%

20

0.4579

Sphingomonas

6424

3.02%

11,854

4.58%

7303

4.11%

16.19

0.5104

Actinomyces

7190

3.38%

42

0.02%

1775

1.00%

8.5714

0.8045

Chryseobacterium

12,515

5.88%

10,284

3.97%

5003

2.81%

20

0.4579

Streptococcus

1886

0.89%

567

0.22%

5230

2.94%

17.143

0.4447

Lacticaseibacillus

0

0.00%

0

0.00%

198

0.11%

5

0.1718

Bifidobacterium

2545

1.20%

95

0.04%

215

0.12%

5.7143

0.4559

Listeria

108

0.05%

492

0.19%

63

0.04%

4.375

0.4968

Thermaerobacter

602

0.28%

125

0.05%

1840

1.03%

14.286

0.2828

Staphylococcus

2073

0.97%

1265

0.49%

1695

0.95%

19.286

0.4386

Prevotella_9

9

0.00%

72

0.03%

1169

0.66%

6.0714

0.2993

Atopobium

0

0.00%

832

0.32%

484

0.27%

11.868

0.105

Pseudomonas

968

0.46%

1706

0.66%

564

0.32%

20

0.3946

Megasphaera

684

0.32%

560

0.22%

18

0.01%

9.0476

0.4329

Limosilactobacillus

362

0.17%

112

0.04%

32

0.02%

4.3697

0.3583

Acinetobacter

439

0.21%

686

0.26%

228

0.13%

19.048

0.2662

Nocardioides

168

0.08%

144

0.06%

15

0.01%

8.9796

0.2541

Microbacterium

82

0.04%

35

0.01%

271

0.15%

4.3697

0.3583

Rothia

218

0.10%

364

0.14%

255

0.14%

5

0.4159

Prevotella

137

0.06%

532

0.21%

34

0.02%

14.464

0.272

Gemella

0

0.00%

0

0.00%

193

0.11%

9.375

0.09501

Veillonella

79

0.04%

33

0.01%

145

0.08%

8

0.2381

Neisseria

0

0.00%

36

0.01%

6

0.00%

4.3651

0.2246

Family

        

Lactobacillaceae

53,393

11.37%

174,613

33.82%

62,312

14.13%

20

0.4579

Sphingomonadaceae

6460

1.38%

62,870

12.18%

7702

1.75%

19.048

0.3889

Bifidobacteriaceae

2669

0.57%

7671

1.49%

45,471

10.31%

18.857

0.2761

Thermaceae

89,775

19.13%

58,435

11.32%

116,838

26.50%

20

0.4579

Bacillaceae

86,450

18.42%

62,594

12.13%

103,376

23.45%

20

0.4579

Enterobacteriaceae

51,166

10.90%

21,916

4.25%

16,169

3.67%

20

0.4579

Xanthobacteraceae

19,049

4.06%

32,338

6.26%

10,359

2.35%

20

0.3946

Prevotellaceae

24,299

5.18%

668

0.13%

1276

0.29%

14

0.4497

Xanthomonadaceae

51,338

10.94%

26,770

5.19%

26,693

6.05%

20

0.3946

Planococcaceae

0

0.00%

14,582

2.82%

365

0.08%

5.7143

0.2215

Corynebacteriaceae

14,391

3.07%

2474

0.48%

734

0.17%

16.837

0.2069

Comamonadaceae

31,882

6.79%

15,256

2.96%

13,486

3.06%

20

0.4579

Actinomycetaceae

7190

1.53%

227

0.04%

2252

0.51%

11.429

0.6521

Weeksellaceae

12,515

2.67%

10,747

2.08%

5003

1.13%

20

0.4579

Microbacteriaceae

0

0.00%

684

0.13%

4208

0.95%

12.976

0.1637

Streptococcaceae

63

0.01%

453

0.09%

5238

1.19%

14.026

0.1718

Staphylococcaceae

1874

0.40%

4544

0.88%

309

0.07%

11.169

0.3445

Propionibacteriaceae

2229

0.47%

2028

0.39%

4694

1.06%

20

0.4579

Listeriaceae

108

0.02%

364

0.07%

2247

0.51%

4.375

0.4968

Micrococcaceae

1515

0.32%

4540

0.88%

960

0.22%

19.048

0.3889

Lachnospiraceae

1250

0.27%

92

0.02%

2329

0.53%

11.169

0.3445

Thermomicrobiaceae

3189

0.68%

2263

0.44%

2553

0.58%

15.952

0.3852

Moraxellaceae

693

0.15%

1901

0.37%

422

0.10%

19.048

0.3258

Paenibacillaceae

3715

0.79%

2771

0.54%

4195

0.95%

18.929

0.2724

Burkholderiaceae

1658

0.35%

1528

0.30%

720

0.16%

14.286

0.5774

Muribaculaceae

0

0.00%

273

0.05%

31

0.01%

6.0952

0.2971

Dermabacteraceae

0

0.00%

1305

0.25%

0

0.00%

5

0.1718

Pseudomonadaceae

968

0.21%

1021

0.20%

564

0.13%

20

0.2742

Veillonellaceae

895

0.19%

374

0.07%

251

0.06%

8.5714

0.4777

Peptostreptococcaceae

671

0.14%

425

0.08%

157

0.04%

7.2619

0.6099

Clostridiaceae

0

0.00%

508

0.10%

0

0.00%

5

0.1718