Table 4 Analysis of commercial Berberine formulations and statistical comparison with HPLC reference method.

From: Sustainable spectrofluorimetric determination of berberine in dietary supplements via Erythrosin B Ion-Pair complexation with mechanistic investigation, Box-Behnken optimization, and green chemistry assessment

Formulation

Method

Mean a

SD

t-test (2.306) b

P value

F-value (6.338) b

P value

θΛ χ

θΥ χ

Berberine Enzymedica

Developed method

100.94

0.97

0.278

0.789

1.727

0.61

-1.46

1.85

Reported method

100.74

1.28

Berberine NOW Foods

Developed method

97.54

0.98

0.032

0.975

1.577

0.669

-1.64

1.6

Reported method

97.56

1.23

  1. a Average of five determinations.
  2. b The values in parenthesis are tabulated values of “t “and “F” at (P = 0.05).
  3. c Bias of ± 2% is acceptable.
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