Fig. 4 | Scientific Reports

Fig. 4

From: Identification of RBX1 as a regulator of LIPT1 transcription and its role in copper-induced cell death in GBM cells

Fig. 4

Analysis of the Upstream Mechanism of LIPT1 Expression in GBM. (A) Co-expression analysis of LIPT1 and its top 100 correlated genes in GBM from UALCAN. (B) Screening for transcription factors targeting LIPT1 and their co-expression with LIPT1 in GBM. (C) Promoter regions with significant binding peaks of GTF2B near LIPT1 in the Cistrome Data Browser ChIP-seq database. (D) Prediction of E3 ubiquitin ligase targeting GTF2B in UbiBrowser 2.0. (E) Protein expression level of RBX1 in normal brain tissue and GBM from UALCAN. (F) Multiple ubiquitination modification sites of GTF2B protein from UbiBrowser 2.0.

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