Fig. 4 | Scientific Reports

Fig. 4

From: H19 enhances pancreatic cancer proliferation and invasion by reducing miR-29c-5p’s inhibitory effects on ATF2/ECM1

Fig. 4The alternative text for this image may have been generated using AI.

H19 promotes pancreatic cancer progression by ceRNA-mediated inhibition of miR-29c-5p. (A) CCK-8 assay shows the proliferation rate (OD450) of pancreatic cancer cells transfected with H19 overexpression plasmid, shH19, miR-29c-5p inhibitor or mimics at 0, 24, 48 and 72 h (mean ± SD, n = 3, *p < 0.05, **p < 0.01, ***p < 0.001.) (B) Quantitative migration ability of each group in the scratch assay (scratch healing rate at 0 and 24 h, *p < 0.05, **p < 0.01, ***p < 0.001.) (C) Transwell invasion/migration assay of each group (crystal violet staining, 5 × 10⁴ cells per well, *p < 0.05, **p < 0.01, ***p < 0.001.)

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