Fig. 7 | Scientific Reports

Fig. 7

From: H19 enhances pancreatic cancer proliferation and invasion by reducing miR-29c-5p’s inhibitory effects on ATF2/ECM1

Fig. 7The alternative text for this image may have been generated using AI.

Expression and clinical significance of ATF2 and ECM1 genes in pancreatic cancer patients. (A) In the Human Protein Atlas database, low expression of ECM1 protein in pancreatic cancer indicates a better prognosis; in the TCGA database, it was found that low expression of ECM1 mRNA has a better survival prognosis; ECM1 mRNA has a good diagnostic effect, with an AUC area under the ROC curve of 0.978; (B) In the TCGA database, the AUC area under the ROC curve of ATF2 mRNA is 0.949, indicating a good diagnostic effect on pancreatic cancer; (C) In the immunohistochemistry of clinical sample pancreatic cancer pathological sections, high expression of ECM1 and ATF2 proteins was found; (D) Correlation between the mRNA expression of ATF2 and ECM1; (E) Subcellular localization of ATF2 and ECM1 in the Human Protein Atlas database.

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