Fig. 4
From: High fat diet remodels the gene regulatory networks in the preoptic area
Comparative results for MofEXC and MofINH in relation to BenINH and BenEXC derived GCN modules and remission DEGs. (A–B) UMAP plots demonstrating the integration between the Moffitt and Bentsen datasets. (C–D) PCC matrices of the BenEXC derived GCN modules in the MofEXC cells (C) and the BenINH derived GCN modules in the MofINH cells (D). The column colors designate different cell types in the Moffit cells. (E–F) Heatmap of the expression of MofEXC subtype markers in BenEXC cells (E) and MofINH subtype markers in BenINH cells (F). Genes (i.e., rows) annotated with the blue bar were downregulated in the Bentsen remission cells, whereas genes designated with a red bar were upregulated in the Bentsen remission cells. Subtype marker expression across all cell types can be found in Fig. S3C–D.
