Table 2 Top 10 most upregulated & downregulated genes based on log2FC from BenINH between day 5 and day 1 in the FGF1 treated mice that were not significant in the Veh treated mice. Note that P denotes p-value, log2FC denotes the average log2FC for the FC=remission(day 5)/diabetic(day 1), Prop1 denotes the proportion of cells expressing the gene in the remission group (day 5), Prop2 denotes the proportion of cells expressing the gene in the diabetic group (day 1), and Padj denotes the bonferroni adjusted p-value.
From: High fat diet remodels the gene regulatory networks in the preoptic area
Gene | p | log2FC | Prop1 | Prop2 | Padj |
|---|---|---|---|---|---|
Gm12728 | 7.08E-08 | 3.917912 | 0.013 | 0.001 | 1.43E-03 |
RP23-340E19.1 | 8.80E-20 | 3.892511 | 0.035 | 0.003 | 1.78E-15 |
Gm29669 | 2.04E-09 | 3.040732 | 0.021 | 0.003 | 4.12E-05 |
Gm7808 | 3.40E-10 | 2.980156 | 0.023 | 0.004 | 6.87E-06 |
Gm29398 | 1.18E-08 | 2.854998 | 0.02 | 0.003 | 2.38E-04 |
Gm21973 | 2.42E-06 | 2.688626 | 0.015 | 0.003 | 4.88E-02 |
Ang4 | 7.21E-15 | 2.687736 | 0.037 | 0.006 | 1.46E-10 |
Gm5160 | 4.59E-10 | 2.659267 | 0.025 | 0.004 | 9.27E-06 |
Igfbpl1 | 1.76E-39 | 2.638586 | 0.1 | 0.02 | 3.55E-35 |
Scrt2 | 9.30E-12 | 2.537884 | 0.032 | 0.007 | 1.88E-07 |
Fmo4 | 1.13E-11 | − 2.91612 | 0.002 | 0.022 | 2.29E-07 |
Gm19272 | 1.09E-06 | − 3.01563 | 0.001 | 0.011 | 2.19E-02 |
Ffar1 | 1.04E-10 | − 3.10959 | 0.002 | 0.019 | 2.09E-06 |
5830416I19Rik | 1.62E-14 | − 3.45106 | 0.002 | 0.027 | 3.26E-10 |
Gm11337 | 7.48E-21 | − 3.56463 | 0.002 | 0.032 | 1.51E-16 |
Ctcflos | 2.24E-53 | − 3.91665 | 0.008 | 0.099 | 4.52E-49 |
Pabpn1 | 5.54E-30 | − 5.1226 | 0.001 | 0.043 | 1.12E-25 |
Gm10800 | 2.24E-09 | − 6.71308 | 0 | 0.011 | 4.53E-05 |
Gm44290 | 1.17E-09 | − 6.82192 | 0 | 0.011 | 2.36E-05 |
Alb | 4.31E-09 | − 6.83346 | 0 | 0.01 | 8.71E-05 |
