Table 1 Demographic and clinic-pathological data for enrolled individuals.

From: Clinical impact of the methylation status of SMAD4 and AKR1B1 genes in a liquid biopsy sample as a prognostic marker for breast cancer

Factors

Control

N = 30

Benign breast lesions

N = 30

Breast cancer

N = 80

Age

   

Median

47

45

50

Mean ± SD

50.7 ± 8

50 ± 8

51.4 ± 8

Menopausal status

   

Pre-menopause

14

15

40

Post-menopause

16

15

40

Pathology status

---

Fibroadenoma (n = 9)

DCIS (n = 33)

IDC (n = 47)

Follicular hyperplasia (n = 10)

Intra-ductal papillomatosis (11)

Clinical stage

---

---

 

Early stage

35

Late stage

45

Histological grade

---

---

 

Low grade

31

High grade

49

Lymph- node involvement

---

---

34

Negative

Positive

ER-status

---

---

 

Negative

41

Positive

39

PgR-status

---

---

 

Negative

39

Positive

41

HER-2neu-status

---

---

 

Negative

52

Positive

28