Table 4 Sensitivities and specificities of investigated parameters for detection of early stages and low grades.

From: Clinical impact of the methylation status of SMAD4 and AKR1B1 genes in a liquid biopsy sample as a prognostic marker for breast cancer

Parameters

Early - stage

Low - grade

AUC

Sensitivity

Specificity

AUC

Sensitivity

Specificity

CEA

0.536

31.43

98.33

0.587

35.48

98.33

CA15.3

0.707

48.57

85.00

0.713

41.94

93.33

SMAD4

1

100.00

100.00

1

100.00

100.00

AKR1B1

0.924

100.00

88.33

0.922

100.00

88.33

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