Abstract
Activities of daily living, including grasping, holding, and pinching, are essential for independence but often become difficult for individuals with cerebrovascular disease owing to upper limb paralysis. We investigated the relationship between adjustability of grasping force (AGF), defined as the ability to adjust grasping force, and upper limb/hand functional performance. Twelve individuals with mild cerebrovascular disorders participated in this preliminary cross-sectional study. Assessments included the AGF task using iWakka, the Fugl-Meyer Assessment, Simple Test for Evaluating Hand Function, Action Research Arm Test (ARAT), and Motor Activity Log (MAL). AGF was quantified using the AGF score, calculated as the absolute error between target and actual grasping force; lower AGF scores indicate better AGF. Partial Spearman’s rank correlations, adjusted for age, revealed that AGF score (isometric section) on the less-affected side was negatively and positively correlated with ARAT and MAL (Quality of Movement) on the less-affected and more-affected sides, respectively. These findings suggest that better AGF on the less-affected side may enhance motor performance on that side but could be associated with lower perceived movement quality on the more-affected side. This highlights the complex role of the less-affected side in post-stroke function and suggests that rehabilitation strategies should consider AGF on both sides of the body.
Data availability
The data that support this study’s findings are available from the corresponding author on reasonable request. The data are not publicly available due to ethical restrictions.
References
Neumann, D. A. Kinesiology of the Musculoskeletal System: Foundations for Physical Rehabilitation (Mosby, 2002).
Fugl-Meyer, A. R., Jääskö, L., Leyman, I., Olsson, S. & Steglind, S. The post-stroke hemiplegic patient. 1. A method for evaluation of physical performance. Scand. J. Rehabil. Med. 7, 13–31 (1975).
Platz, T. et al. Reliability and validity of arm function assessment with standardized guidelines for the Fugl-Meyer test, action research arm test and box and block test: A multicentre study. Clin. Rehabil. 19, 404–411 (2005).
Kaneko, T. & Muraki, T. Development and standardization of the hand function test. Bull. Allied Med. Sci. Kobe. 6, 49–54 (1990).
Uswatte, G., Taub, E., Morris, D., Vignolo, M. & McCulloch, K. Reliability and validity of the upper-extremity motor activity log-14 for measuring real-world arm use. Stroke 36, 2493–2496 (2005).
Takahashi, K. et al. Reliability and validity of the motor activity log in Japan. Jpn. Occup. Ther. Res. 28, 628–636 (2009). (in Japanese).
Tiffin, J. Purdue Pegboard Examiner Manual (Science Research Associates, Chicago 1968).
Kaneno, T. et al. Assessing the adjustability of grasping force using the iWakka in elderly individuals. J. Phys. Ther. Sci. 29(12), 2215–2219 (2017).
Kaneno, T. et al. The error range of the assessment method of grip force adjustment ability. Rigakuryoho Kagaku. 32, 117–121 (2017). (in Japanese).
Demartino, A. M., Rodrigues, L. C., Gomes, R. P. & Michaelsen, S. M. Hand function and type of Grasp used by chronic stroke individuals in actual environment. Top. Stroke Rehabil. 26, 247–254 (2019).
Kitsos, G. H., Hubbard, I. J., Kitsos, A. R. & Parsons, M. W. The ipsilesional upper limb can be affected following stroke. Sci. World J. 2013, 684860 (2013).
Michielsen, M. E., Selles, R. W., Stam, H. J., Ribbers, G. M. & Bussmann, J. B. Quantifying nonuse in chronic stroke patients: A study into paretic, nonparetic, and bimanual upper-limb use in daily life. Arch. Phys. Med. Rehabil. 93, 1975–1981 (2012).
Taub, E. et al. A placebo-controlled trial of constraint-induced movement therapy for upper extremity after stroke. Stroke 37, 1045–1049 (2006).
Brunnstrom, S. Motor testing procedures in hemiplegia: Based on sequential recovery stages. Phys. Ther. 46, 357–375 (1966).
Kitamura, T. Mini-Mental State (MMS). In: Assessment Manual of Intellectual Function for the Demented Elderly (eds Otsuka, T. & Homma, A.) 35–38 (World Planning Co., Ltd., Tokyo, (1991). (in Japanese).
Data Management Service of the Uniform Data System for Medical, R. & The Center for Functional Assessment, R. Guide for Use of the Uniform Data Set for Medical Rehabilitation. Version 3.0 (State University of New York, 1990).
Oldfield, R. C. The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia 9, 97–113 (1971).
Kaneno, T., Sato, A. & Akizuki, K. The characteristics of adjustability of grasping force in healthy elderly people. Rehabil. Eng. 34, 156–162 (2019). (in Japanese).
Kaneno, T. et al. A comparative study of adjustability of grasping force between young people and elderly individuals. Asian J. Occup. Ther. 15, 69–75 (2019).
Bertrand, A. M., Mercier, C., Shun, P. L., Bourbonnais, D. & Desrosiers, J. Effects of weakness on symmetrical bilateral grip force exertion in subjects with hemiparesis. J. Neurophysiol. 91, 1579–1585 (2004).
Colebatch, J. G. & Gandevia, S. C. The distribution of muscular weakness in upper motor neuron lesions affecting the arm. Brain 112, 749–763 (1989).
Barry, A. J. et al. Survivors of chronic stroke experience continued impairment of dexterity but not strength in the nonparetic upper limb. Arch. Phys. Med. Rehabil. 101, 1170–1175 (2020).
Maenza, C., Good, D. C., Winstein, C. J., Wagstaff, D. A. & Sainburg, R. L. Functional deficits in the less-impaired arm of stroke survivors depend on hemisphere of damage and extent of Paretic arm impairment. Neurorehabil Neural Repair. 34, 39–50 (2020).
Acknowledgements
The authors would like to express their gratitude to the participants of this study. This work was supported by JSPS KAKENHI Grant Number JP 18K17762.
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TK: Study conception and design, Data collection, Analysis and interpretation of results, Manuscript preparation, and funding acquisition.KK: Study conception and design, Data collection, Analysis and interpretation of results, and manuscript preparation.TY: Data collection, Analysis and interpretation of results, and manuscript preparation.TT: Data collection, Analysis and interpretation of results, and manuscript preparation.TS: Data collection, Analysis and interpretation of results, and manuscript preparation.AS: Study conception and design, Analysis and interpretation of results, and manuscript preparation.KA: Study conception and design, Analysis, and interpretation of results, and manuscript preparation.YM: Study conception and design, Analysis, and interpretation of results, and manuscript preparation.All authors read and approved the final manuscript.
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The informed consent was obtained, by explaining the purpose and content of this study orally and in writing to individuals with cerebrovascular disease who met the inclusion criteria. Ultimately, 12 people who agreed to participate in this study were selected as the participants. This study protocol was approved by the Ethics Review Committees of Mejiro University (approval no. 19–045) and Tokyo Metropolitan University (approval no. 22046).
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Kaneno, T., Kawahara, K., Yabe, T. et al. Relationship between adjustability of grasping force and upper limb/hand function in individuals with cerebrovascular disorders. Sci Rep (2026). https://doi.org/10.1038/s41598-026-38384-z
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DOI: https://doi.org/10.1038/s41598-026-38384-z
