Fig. 3 | Scientific Reports

Fig. 3

From: aFGF rescues high glucose-induced senescent fibroblasts and improves diabetic wound healing by regulating SIRT1/STAT3 pathway

Fig. 3The alternative text for this image may have been generated using AI.

aFGF enhances the proliferation and migration of HG-induced L929 fibroblasts. (A) The relative proliferation of L929 induced by different concentrations of aFGF was measured by CCK-8 (n = 3). (B) Representative EDU staining images of L929 after 72 h of exposure to HG or HG and aFGF (bar scales = 200 μm). (C) Quantitative analysis of EDU staining (n = 3). (D) Quantitative analysis of migrated cells under the transwell chamber in each group (n = 3). (E) Representative images of migrated L929 at the outer bottom of the transwell chamber stained by crystal violet in indicated groups. (bar scales = 200 μm). Results are presented as the mean ± SD. ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05. NS, non-significance vs. the control group.

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