Table 3 Results of statistical analysis of immunohistochemical scores for ER, HIF-1α, and OTR expression in ovarian tissue.

From: Cannabidiol mitigates secondary genital injury after thoracic trauma by regulating systemic inflammation and hormone receptor signaling

Marker

Group

Mean ± SD

P value

ER

Control

58.38 ± 3.82

 

TRA

16.88 ± 2.61

 < 0.001***

TRA + CBD

41.25 ± 2.61

 < 0.001***

CBD

55.88 ± 3.72

NS

HIF-1α

Control

4.63 ± 1.60

 

TRA

14.88 ± 3.80

 < 0.001***

TRA + CBD

6.13 ± 0.83

NS

CBD

2.88 ± 0.64

NS

OTR

Control

14.25 ± 2.96

 

TRA

60.50 ± 2.88

 < 0.001***

TRA + CBD

20.75 ± 1.67

 < 0.001***

CBD

11.88 ± 1.64

NS

  1. Data are presented as mean ± SD (n = 8 per group). Statistical significance was determined by one-way ANOVA followed by Tukey’s post-hoc test. NS: not significant. p-values were calculated relative to the control group.