Table 4 Toxicity prediction of seven top-scored compounds, predicted through StopTox.
From: Molecular docking and dynamics reveal novel CDK6 inhibitors for targeted glioblastoma therapy
Codes | Acute inhalation toxicity | Acute oral toxicity | Acute dermal toxicity | Eye irritation and corrosion | Skin sensitization | Skin irritation and corrosion |
|---|---|---|---|---|---|---|
CCL | Non-toxic | Toxic | Non-toxic | Non-toxic | Non-sensitizer | Negative |
21 | Non-toxic | Toxic | Non-toxic | Non-toxic | Non-sensitizer | Negative |
69 | Non-toxic | Toxic | Non-toxic | Toxic | Non-sensitizer | Negative |
34 | Non-toxic | Toxic | Non-toxic | Toxic | Non-sensitizer | Negative |
57 | Non-toxic | Toxic | Non-toxic | Toxic | Non-sensitizer | Negative |
93 | Non-toxic | Toxic | Non-toxic | Toxic | Non-sensitizer | Negative |
54 | Non-toxic | Toxic | Non-toxic | Toxic | Non-sensitizer | Negative |
42 | Non-toxic | Toxic | Non-toxic | Toxic | Non-sensitizer | Positive |
